Panik hurt himself in the first inning as he tried to beat out a grounder to first baseman Ryan Howard, who couldn't field the ball cleanly but eventually fed it to pitcher Roberto Hernandez covering the bag. Hernandez barely beat Panik, who rolled his ankle as he stepped on the right edge of the base.
Panik jogged gingerly back to the dugout and ran at a similar pace when he took his position for the bottom of the first inning. One inning later, Ehire Adrianza replaced Panik at second.
Chris Haft is a reporter for MLB.com. Read his blog, Haft-Baked Ideas, and follow him on Twitter at @sfgiantsbeat. This story was not subject to the approval of Major League Baseball or its clubs.