Pagan has had right knee soreness since April. He also missed last Sunday and Tuesday's games with a sprained AC joint in his left shoulder, which he sustained while diving for a ball last Saturday against Miami.
Pagan, batting .316 with three home runs and 16 RBIs, does not have an RBI in his last 18 games.
Gregor Blanco (.143, no home runs, six RBIs) took over center field and leadoff duties Sunday.
Willie Bans is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.