In 2011, the club persevered without its heart and soul behind the plate, Buster Posey, and racked up 86 wins and a second-place finish in the National League West.
This season, following the announcement of Melky Cabrera's 50-game suspension, San Francisco rolled off 30 wins in its next 45 contests to capture the division crown.
So what's a 2-0 deficit in a best-of-five series?
"Obviously, the cliche is to say 'It's just another game,' but I feel like 'just another game' doesn't count when you're talking about postseason to begin with," said Giants right-hander Ryan Vogelsong, who will start Game 3 on Tuesday, airing at 2:30 p.m. PT on TBS. "Things are [magnified] a little bit and if you talk about 0-2, being down in the series, you can't really say it's just another game, either.
"In the same sentence, you still have to throw strikes and get guys out and I think the best way to do that is one pitch at a time, one out at a time, one game at a time."
Giants manager Bruce Bochy took note of his club's relaxed state as it traveled across the country Monday.
"We know where we are, and we have our work cut out," Bochy said. "It is the best of five and we'll come out ready to go [Tuesday]."
Even on their run to a World Series title in 2010, the Giants never had their backs up against the wall like this. That October, the club never trailed in a series and only lost four times on its way to a championship. Now, the Giants stare in the eye all of the statistics that suggest they stand no chance. In 21 previous occasions, no National League team has ever recovered from a 2-0 deficit in the National League Division Series. The Reds also haven't dropped three straight home games all season.
"Sure, it's difficult, but it's the best out of five," Bochy said. "You have to win that third game. We are alive, and more than anything, you have to have the attitude, 'Never say die' and you come out here, you play hard and you see what happens."