The Friday afternoon dedication ceremony celebrated the 22nd perfect game in Major League Baseball history and first in franchise history, with the plaque neighboring similar ones celebrating Barry Bonds, Willie Mays, the 2002 National League champion Giants and the '10 World Series champions.
"It's really cool to know this is going to be here forever," Cain said to the crowd of approximately 300 fans. "I can't thank everybody enough to have the opportunity to do what I've done in a Giants uniform since '02, and to be here 10 years later in this situation."
Cain recognized Gregor Blanco for his diving catch in the seventh inning of the game, as well as Buster Posey for "doing all the work" in the game.
The Giants also honored Cain's achievement on the field before the game against the Rockies, with Giants broadcasters Dave Flemming and Duane Kuiper leading a ceremony that included Cain's family and former coaches plus members of the Giants organization.
"He has epitomized what being a Giant means, and that's what we're here to celebrate tonight," Flemming said.
The AT&T Park crowd watched a special tribute video from the game, as well as congratulatory video messages from fellow perfect-game pitchers Roy Halladay, Philip Humber and Mark Buehrle.
Giants president and chief executive officer Larry Baer presented Cain with a special present -- an offseason trip to Hawaii, where he will play a round of golf with PGA pro Dustin Johnson, as well as a special commemorative golf club. Hours before his perfect game, Cain teed off from home plate with Johnson, who was at the ballpark for a special promotional event before the U.S. Open.
Cain took the podium to thank fans for their support before and after the historic game, as well as the Giants organization for which he has played since he was drafted in 2002.
"They gave me an opportunity out of high school at 17 years old and took a big bet on me," Cain said. "And here I am 10 years later thanking these guys for taking that leap of faith."
Cain also presented Blanco with a special framed photo and personalized note from the perfect game in the pregame ceremony.
"It's a special night, and it's special what the Giants have done out there," manager Bruce Bochy said. "It's going to be out there forever. I'm sure that's gone through Matt's mind. As long as the Giants have been in existence, it's never been done, and now he's got a plaque out there that you can see anytime. It's historic, and it was a nice event that they had out there."
Jay Lee is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.