Huff had missed the past three games, a doubleheader in New York against the Mets on Monday and Tuesday night's 9-2 loss against the Reds. He last played at New York on Saturday, making his first career appearance at second base, and is hitting just .182 on the season. He has had just one hit in his last 15 plate appearances.
"He had an episode of anxiety. He got some treatment and will continue to get treatment," said Bochy prior to Wednesday night's game. "We can't keep going short, so we think at this time the best thing is to go ahead and make this move and put him on the 15-day disabled list."
The Giants purchased the contract of infielder Joaquin Arias from Triple-A Fresno to replace Huff on the roster. Arias played Tuesday night as the Grizzlies beat Tacoma, 11-5, going 3-for-3 with two doubles, two RBIs and a run scored.
Bochy said he expects Huff to join the team in San Francisco on Friday when it opens a three-game series at AT&T Park against San Diego. Bochy said the rest of the team did not know the reason why Huff was away.
"We are going to do everything we can to help the player and that's the case with Aubrey," said Bochy.
Bochy said he was unaware of Huff having dealt with anxiety attacks previously.
Huff is not the first Major League player to deal with an anxiety disorder. Cincinnati All-Star first baseman Joey Votto, the National League MVP in 2010, spent time on the DL in 2009 with anxiety-related issues. Milwaukee pitcher Zack Greinke and former San Diego and St. Louis infielder Khalil Greene are other notable players who have dealt with anxiety.
It's a disorder that players as well as society in general are more willing to speak about publicly.
"I'm sure it was there when I played, but you probably weren't as likely to talk about it openly," said Bochy. "Now there are different players that deal with different pressures in life, whether it's at home and personal or on the ballfield. It happens occasionally."
Huff jumped into the arms of catcher Buster Posey following the Giants' World Series victory against Texas in 2010, a joyous moment caught in still photography. Following Tuesday night's game, Posey voiced his concern for his teammate when the subject was brought up.
"We've got a job to do when we come to the park," said Posey. "Obviously we miss him. He's a big part of this team and I hope everything is all right."
Kevin Goheen is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.